![]() Molecular assessment of differences in the duodenal microbiome in subjects with irritable bowel syndrome. Giamarellos-Bourboulis E, Tang J, Pyleris E, et al. Small intestinal bacterial overgrowth in rosacea: clinical effectiveness of its eradication. The place of antibiotics in management of irritable bowel syndrome: a systematic review and meta-analysis. Abnormal intestinal motor patterns explain enteric colonization with gram-negative bacilli in late radiation enteropathy. ![]() The prevalence of overgrowth by aerobic bacteria in the small intestine by small bowel culture: relationship with irritable bowel syndrome. Pyleris E, Giamarellos-Bourboulis EJ, Tzivras D, et al. This study showed that abscent phase III MMCs is a risk factor for bacterial overgrowth. Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and/or fungal overgrowth. Jacobs C, Coss Adame E, Attaluri A, et al. Irritable bowel syndrome and small intestinal bacterial overgrowth. Small intestinal bacterial overgrowth syndrome. Risk factors for small bowel bacterial overgrowth and diagnostic yield of duodenal aspirates in children with intestinal failure: a retrospective review. Gutierrez IM, Kang KH, Calvert CE, et al. Gastrointestinal bacterial overgrowth: pathogenesis and clinical significance. Papers of particular interest, published recently, have been highlighted as: In this review, we will discuss the current evidence for the diagnosis and treatment of SIBO, which includes (1) elimination/modification of the underlying causes, (2) induction of remission (antibiotics and elemental diet), and (3) maintenance of remission (promotility drugs, dietary modifications, repeat or cyclical antibiotics). Clearly, there is a strong need to develop a systematic approach for the management of SIBO and to perform multicenter clinical trials for the treatment of SIBO. Treatment of SIBO remains empirical generally, broad spectrum antibiotics are recommended for 2 weeks (amoxicillin, rifaximin, ciprofloxacin, etc.) but evidence for their use is fair. However, there is a lack of standardization of these tests and their interpretation. Several tests have been proposed, including the glucose breath test, lactulose breath test, small intestinal aspiration and culture, and others. Although known for many decades, there is a lack of consensus and clarity regarding the natural history and methods for its diagnosis. doi: 10.Small intestinal bacterial overgrowth (SIBO) is characterized by an excessive amount of bacteria in the small intestine and a constellation of symptoms that include bloating, pain, gas, and diarrhea. Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome: A Bridge between Functional Organic Dichotomy. Impact of Small Intestine Bacterial Overgrowth on Response to a Nutritional Intervention in Bangladeshi Children from an Urban Community. Gaffar SMA, Sarker SA, Mahfuz M, Donowitz JR, Ahmed T. Systematic review with meta-analysis: rifaximin is effective and safe for the treatment of small intestine bacterial overgrowth. Meta-analysis: antibiotic therapy for small intestinal bacterial overgrowth. Reliability of jejunal culture and inadequacy of breath hydrogen testing. The diagnosis of small bowel bacterial overgrowth. Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus. Small intestinal bacterial overgrowth: a comprehensive review. Iron, anaemia, and inflammatory bowel diseases. Review article: small intestinal bacterial overgrowth-prevalence, clinical features, current and developing diagnostic tests, and treatment. Small intestinal bacterial overgrowth (SIBO) in irritable bowel syndrome: frequency and predictors. Lactose malabsorption in the elderly: role of small intestinal bacterial overgrowth. Almeida JA, Kim R, Stoita A, Mciver CJ, Kurtovic J, Riordan SM.
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